Impact of Managed Therapy on Adherence to Medications Used to Treat Multiple Sclerosis and Related Comorbid Conditions
Results: Mean proportion of days covered rates improved significantly in the group managed for at least 6 months compared with those who were less managed. Positive screenings for fatigue and depression reduced adherence in the less-managed group but not in patients with longer participation in the program.
Conclusions: Overall, the CCMS program significantly increased adherence to MS medications. This improved adherence was not negatively impacted by positive screenings for fatigue and depression.
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28 comments to “Impact of Managed Therapy on Adherence to Medications Used to Treat Multiple Sclerosis and Related Comorbid Conditions”
Adherence to MS medications was measured as the proportion of days covered, with propensity scores used to match the CCMS intervention group to the less-managed comparison group. The impact of program participation on the relationship between depression or fatigue and adherence over time was a separate analysis.
This improved adherence was not negatively impacted by positive screenings for fatigue and depression.
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